Emhlabeni we-autoration elebhu, ukuthola izixazululo ezilungiselela ukusebenza kahle nokunemba kubalulekile. Ngokuqala kwepuleti eline-96-elinempilo eligcwele, abacwaningi nososayensi bavule amandla ezingeni elisha le-automation. Lawa mapuleti anikela ngezici ezahlukahlukene ezithuthukisa ukusebenza kokuhlaziya, ukuphepha okuphephile, nokuhlanganiswa komthungo nezinhlelo zamarobhothi. Kule bhulogi, sizokwelulwa imininingwane yepuleti eline-96 elinempilo eligcwele futhi lixoxe ngezinzuzo zalo zezinhlelo zokusebenza zelebhu.
Thuthukisa ukusebenza kahle:
Enye yezinzuzo ezivelele ezinamapuleti anezinkinga ezi-96-agcwele yikhono lazo lokwandisa ukusebenza kahle. Amapuleti aklanyelwe ukulingana kwi-ANSI ye-ANSI Footprint futhi ayabambeke ezinhlelweni ezenzakalelayo, enza kahle ukusetshenziswa kwendawo yelebhu ebalulekile. Abaphenyi manje base benza inani elikhulu le-ASS ngasikhathi sinye, ngcono kakhulu ukukhishwa kwemali, ukukhiqiza, kanye nokusebenza kwezindleko.
Thuthukisa ukusebenza kahle kwe-PCR:
Iphrofayili ephansi yepuleti eline-96-eligcwele eligcwele lisiza ukunciphisa isikhala esifile futhi lithuthukise ukusebenza kahle kwe-polymerase chain reaction (PCR). I-PCR inqubo esemqoka esetshenziselwa ukukhulisa i-DNA, futhi noma yikuphi ukuhlukahluka kokushisa ngaphakathi kwepuleti kungahle kuholele ekukhulisweni okungahambisani. Ukusetshenziswa kwalawa mapuleti kuqinisekisa ukudluliswa kokushisa okufanayo, kunciphisa amathuba okushisa umehluko, futhi ekugcineni kwandisa ukwethenjwa kanye nokunemba kwemiphumela ye-PCR.
Ukuphathwa kwe-robot okuthuthukisiwe:
Ngokuhlanganiswa komthungo nezinhlelo ezenzakalelayo, ipuleti le-96-kahle eligcwele linikezwa njenge-superplate, okungukuqina okuphindwe kane. Lesi sici esibucayi siqinisekisa ukuphathwa kahle kwamarobhothi futhi sinciphise ubungozi bezingozi namaphutha ngesikhathi sokudluliswa kwepuleti. Imishini ezenzakalelayo yokuhamba ngokuthembekile, izinhlobo nezinhlobo zamapuleti, okuholela ekusebenzeni okubushelelezi futhi kunciphise isikhathi sokuphumula.
Kuvikelwe ngokuphephile ngaphandle kokuhwamuka:
Imiphetho ephakanyisiwe nxazonke ngakunye epuletini yenza lula uphawu oluvikelekile. Lolu mbono lubalulekile lapho uphatha amasampula abucayi adinga ukulawula okuqondile kwevolumu nemvelo. Abaphenyi bangaphumula kalula ukwazi amasampula abo abalulekile avikelekile ekungcolisweni nasekuhambweni, eqinisekisa imiphumela yokuhlola engaguquki futhi ethembekile.
Ukudluliselwa kokushisa okungaguquki:
Ngokusebenzisa kahle izindonga ezingezincishiwe kahle, isiketi esigcwele esingu-96 sinikeza ukuhanjiswa okuphezulu nokungaguquguquki phakathi komthombo ngamunye. Lokhu kufana kubucayi kokucabanga okudinga ukulawulwa kokushisa okuqondile, njengokuhamba ngebhayisikile okushisayo, ukusabela kwe-enzymatic, ne-protein crystallization. Amakhono okudlulisa afudumele okushisa avuselela anika amandla imiphumela ethembekile nezenzekayo, anciphise ukukhetha kokuhlola kanye nokwenza ngcono idatha yedatha.
Isikhathi sePosi: Jun-25-2023